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The case for a-posteriori statistics

Presently, measurements are made and statistics derived during simulated development. A case can be made for measurements made with a separate program.

  • Posted by randalk
  • Published: 2006-02-04

Advances in growth cone direction models

A preview comparing the results obtained with the old and new direction models for turns in neurites.

  • Posted by randalk
  • Published: 2005-12-01

Finally some attention to synapses

Simulations have finally reached the stage where direct attention is given to the generation of specific synapse types.

  • Posted by randalk
  • Published: 2005-09-07

Some typical branching events

New branch definitions and branch events at segments other than terminal segments improve the realism of the development of neuronal arbor.

  • Posted by randalk
  • Published: 2005-08-31

Optimizing with the van Pelt and Uylings method

Van Pelt and Uylings published several methods of optimizing model parameters to achieve realistic fibre data distributions during neuronal development. Here, the optimization is applied for data obtained by Ger Ramakers.

  • Posted by randalk
  • Published: 2005-08-29

The default distribution of neuron types matches the data

Experimentally observed distributions of neuron types in culture are now used as the default for network generation.

  • Posted by randalk
  • Published: 2005-07-19

Proportions of types of neuron can be specified

The network generation framework now accepts the specification of the proportion of each type of neuron in a generated network.

  • Posted by randalk
  • Published: 2005-06-20

Two Branch Types: Forks and Main-Daughter Bifurcations

Bifurcations during the growth of dendrites and axons may now take two different forms.

  • Posted by randalk
  • Published: 2005-06-10

First results for axons with free turns

These are some first results of network generation (with only four neurons) when dendritic growth applies the Samsonovich hypothesis that turns return arbor growth to a somatic normal vector, but axonal growth exhibits turns that are free of such constraints.

  • Posted by randalk
  • Published: 2005-06-06

Choosing a data fitting approach

A 2002 paper by van Pelt and Uylings describes four different approaches to parameter estimation from data for use with their model of dendritic branching. Specific considerations apply to the choice for one of the methods when simulating network growth according to data by Ger Ramakers.

  • Posted by randalk
  • Published: 2005-06-06

Preliminary result: Broader dispersion of axon growth significantly affects connection structure

Preliminary tests with axon growth functions that do not include the dendritic assumptions of turn directions that were based on work by Samsonovich lead to significantly different connection structure in generated networks.

  • Posted by randalk
  • Published: 2005-06-02

Future Directions suggested after fitting with linear polynomial functions

A subsection about possible future directions has been added to the presentation of results for the simulation of network development with linear bifurcation and elongation functions fitted to experimental data.

  • Posted by rak
  • Published: 2005-04-27

Initialization of pyramidal cell morphology

A reimplementation of the initialization code for pyramidal cells generated with the network generation framework is in the works.

  • Posted by randalk
  • Published: 2005-04-04

A Form for Collaborative Discussions

A Forum is now open on the CASPAN site where collaborative discussions can take place. The forum is open to CASPAN members only. All CASPAN group members can post new discussion items or respond to items on the forum.

  • Posted by rak
  • Published: 2005-03-31

CASPAN site opened

The CASPAN collaboration site has been opened for member registration.

  • Posted by rak
  • Published: 2005-03-07
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